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The defending champion and five-time Wimbledon winner lost 6-2, 1-6, 6-4 in the fourth round. The early exits by favored players at the tournament leaves relative unknowns looking to see how far they can go.

The Jan. 6 investigation has brought new attention to tumult at the watchdog agency for the Department of Homeland Security. Now its Inspector General is under fire from multiple directions.

The roots music maverick did something rare in the streaming era: landed an album that's only available on CD, cassette and LP — without his name on the sleeve — in the top five of the albums chart.

The number of people seeking jobless benefits shot up again last week, as 6.6 million more of the unemployed filed first-time claims. Much of the economy has shut down, leaving millions out of work.

Host, Executive Producer, Idea Man, and Top Dog of State of the Re:Union, Al Letson has received national recognition and built a devoted fan base with soul-stirring, interdisciplinary work. He established himself early in his career as a heavyweight in the Poetry Slam Movement, which garnered artistic credibility and renown. Performing on a number of national, regional and local stages including HBO's Def Poetry Jam, CBS's Final Four PreGame Show and commercial projects for Sony, the Florida Times Union, Adobe Software, and the Doorpost Film Project, Al has honed his professional voice and artistic sensibilities into a unique brand that is all his own. After winning the Public Radio Talent Quest, Al received a grant from the Corporation for Public Broadcasting to create three episodes of his public radio show concept State of the Re:Union. His company finished their first grant in August of 2009 and has just been awarded one of the largest public radio grants every given to a single project to produce a full season of shows.

A new report shows tuberculosis was one of the top 10 causes of death worldwide in 2015, and that the United Nations health body is not on track to meet its goals for reducing deaths from the disease.

NPR.org's new interactive scorecard suggests that President Obama may have a somewhat easier path to 270 electoral votes than Mitt Romney, needing to win fewer states. But that's not a given. As you play, you'll be able to come up with plenty of combinations that would get Romney over the top.

Airbus, the second-largest aircraft-maker, says that in 20 years China will overtake the U.S. as the world's top aviation market. The estimates are similar to projections issued by Airbus' bigger rival, Boeing, earlier this year.

The last time the U.S. ranked No. 1 in a key economic index was 2008. Key issues cited in the 2016 report: America's problems with its infrastructure, health and primary education systems.

A Russian missile slammed into the top floor of an apartment building in the capital, killing at least one person and injuring several others.